Fungi - Candida albicans - Biological Classification & General Actual Biology - Non-Eaborate Posts - Post 8

Pharmaceutics


Fluconazole is used for maintenance therapy; amphotericin B and flucytosine are used for induction. ERG11-targeting azole efficacy can be reduced by mutations or by ERG11 copy increases. Pharmaceutic strategies include combination therapy and high-dose azole regimens in some settings. Drug development explores compounds that target pathways other than Erg11/CYP51. Formulation (oral fluconazole) supports outpatient maintenance therapy in resource-limited settings. Resistance informs drug policy on prophylaxis and long-term maintenance dosing

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