Fungi - Candida albicans - Non-Eaborate Posts - Post 6

Medicine


ERG11 mutations correlate with clinical fluconazole treatment failures. Laboratories sequence ERG11 and run susceptibility tests to guide therapy. For resistant infections clinicians may use echinocandins or amphotericin B. Management includes source control, removal of devices, and stewardship. Outcomes depend on host immune status and timely antifungal switvh. Hospital surveillance tracks ERG11 mutation prevalence regionally. Public health guidelines adapt as resistance patterns shift.

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