Fungi - Candida albicans - Telomere Research Descriptive Posts - Non-Elaborate Posts - Post 2
While the direct link between ERG11 mutations and telomere function is not fully elucidated, it is plausible that disruptions in sterol metabolism could indirectly affect telomere maintenance. This could occur through alterations in membrane fluidity, which might impact the localization or activity of proteins involved in telomere replication and protection. Furthermore, the cellular stress induced by azole exposure and subsequent ERG11 mutation could trigger changes in telomere dynamics.
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