Fungi - Candida albicans - Telomere Research Descriptive Posts - Post 10
For example, if ERG11 mutations lead to increased DNA damage or impaired DNA repair, drugs that enhance DNA repair mechanisms could be beneficial. Similarly, if ERG11 mutations affect the expression of genes involved in cell cycle regulation, drugs that modulate cell cycle progression could be effective. A comprehensive understanding of the nuclear biology of ERG11-mutated Candida albicans is essential for developing targeted and effective antifungal therapies.
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