Fungi - Candida auris - Non-Elaborate Posts - Post 5

 

Pharmaceutics


High fluconazole resistance has focused drug developers on alternatives. Echinocandins are frontline for many invasive C. auris infections; new azoles are being tested. Pharmaceutical R&D explores drugs that bypass Erg11 or avoid efflux susceptibility. Formulation and. PK/PD modelling optimize exposures to try to overcome reduced susceptibility. Companion diagnostics for rapid susceptibility testing are in commercial development. Drug repurposing screens and combination strategies are under investigation for C. auris.

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Fungi - Candida auris - Non-Elaborate Posts - Post 2

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